DETERMINANTS OF MOSAIC CHROMOSOMAL ALTERATION FITNESS

Determinants of mosaic chromosomal alteration fitness

Abstract Clonal hematopoiesis (CH) is characterized by the acquisition of a somatic mutation in a hematopoietic stem cell that results in a clonal expansion.These driver mutations can be single nucleotide variants in cancer driver genes or larger structural rearrangements called mosaic chromosomal alterations (mCAs).The factors that influence the v

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Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity.

Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype "waist circumference for a given body mass index (WC(BMI))", a proxy measure of visceral adiposity, is deemed necessary.Hence, the objective of the present study was to assess the association between dietary factors and prospecti

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